Prostaglandin E1 Alcohol
货号：
13020-500ug 基本售价：
364.0 元 规格：
500 ug
产品信息
概述| 货号 | 13020-500ug |
| 描述 | Prostaglandin E1(PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 µg/ml.1,2 Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 µg.1PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively.3 |
| 别名 | 1-hydroxy Prostaglandin E1;PGE1Alcohol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Nizankowska, E.,Sheridan, A.Q.,Maile, M.H., et al. Bronchodilatory properties of 2-decarboxy-2-hydroxymethyl prostaglandin E1. Prostaglandins 29, 349-362 (1985).
2.Gardiner, P.J.,Copas, J.L.,Schneider, C., et al. 2-Decarboxy-2-hydroxymethyl prostaglandin E1 (TR4161), a prostaglandin bronchodilator of low tracheobronchial irritancy. Prostaglandins 19, 349-370 (1980).
3.Kiriyama, M.,Ushikubi, F.,Kobayashi, T., et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. British Journal of Pharmacology 122, 217-224 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 340.5 |
| 分子式 | C20H36O4 |
| CAS号 | 21562-57-2 |
| 稳定性 | ≥ 2 years |
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