SR 16584
货号：
10683-1mg 基本售价：
364.0 元 规格：
1 mg
产品信息
概述| 货号 | 10683-1mg |
| 描述 | Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the α3β4 nAChR subtype (IC50 = 10.2 μM).1 It shows selective binding of the α3β4 subtype compared to the α4β2 and α7 subtypes (Ki values of 0.508, >100, and >100 μM, respectively), indicating that it should be a useful tool for receptor subtype studies.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zaveri, N.,Jiang, F.,Olsen, C., et al. Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. Journal of Medicinal Chemistry 53, 8187-8191 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 270.4 |
| 分子式 | C17H22N2O |
| CAS号 | 1150153-86-8 |
| 稳定性 | ≥ 2 years |
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