MTSEA
货号：
9002267-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 9002267-10mg |
| 描述 | Methanethiosulfonates (MTSs) are sulfhydryl-reactive compounds that form mixed disulfide linkages and are commonly used to study cysteine residues on proteins. MTSEA is a positively charged sulfhydryl-specific reagent that reacts with substituted cysteines. It can provide functional information about relative positions of amino acids within a protein and can be used to probe binding site electrostatic interactions.1,2,3 |
| 别名 | 2-Aminoethyl methanethiosulfonate;Methanethiosulfonate Ethylammonium; |
性能| 供应商 | Cayman |
| 应用文献 |
1.OReilly, J.P., and Shockett, P.E. Time- and state-dependent effects of methanethiosulfonate ethylammonium (MTSEA) exposure differ between heart and skeletal muscle voltage-gated Na(+) channels. Biochem.Biophys.Acta. 1818(3), 443-447 (2012).
2.Li, R.A.,Tsushima, R.G.,Kallen, R.G., et al. Pore residues critical for μ-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis. Biophysical Journal 73(4), 1874-1884 (1997).
3.Lang, R.J.,Harvey, J.R., and Mulholland, E.L. Sodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caeca. British Journal of Pharmacology 139(6), 1153-1163 (2003).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 236.1 |
| 分子式 | C3H9NO2S2 • HBr |
| CAS号 | 16599-33-0 |
| 稳定性 | ≥ 2 years |
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