D-myo-Inositol-1,4,5-triphosphate (potassium salt)
货号：
60960-100ug 基本售价：
350.0 元 规格：
100 ug
产品信息
概述| 货号 | 60960-100ug |
| 描述 | D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate.1,2 It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium.2,3 |
| 别名 | Ins(1,4,5)-P3 (potassium salt);1,4,5-IP3 (potassium salt); |
性能| 供应商 | Cayman |
| 应用文献 |
1.Streb, H.,Irvine, R.F.,Berridge, M.J., et al. Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 306, 67-69 (1983).
2.Yoshida, Y., and Imai, S. Structure and function of inositol 1,4,5-triphosphate receptor. Japanese Journal of Pharmacology 74, 125-137 (1997).
3.Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual Reviews of Pharmacology and Toxicology 36, 481-509 (1996).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 534.4 |
| 分子式 | C6H12O15P3 • 3K |
| CAS号 | 103476-24-0 |
| 稳定性 | ≥ 1 year |
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