A-23187 (calcium magnesium salt)
货号：
22030-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 22030-1mg |
| 描述 | A-23187 is a divalent cation ionophore. While more selective for Mn2+, it is commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways.1 A-23187 is also used to produce apoptosis through calcium overload, as occurs during hypoxic or oxidative stress.2,3 |
| 别名 | Calcimycin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sullivan, T.J., and Parker, C.W. Pharmacologic modulation of inflammatory mediator release by rat mast cells. Am. J. Pathol. 85(2), 437-464 (1976).
2.Maecker, H.T.,Hedjbeli, S.,Alzona, M., et al. Comparison of apoptosis signaling through T cell receptor, Fas, and calcium ionophore. Exp. Cell Res. 222(1), 95-102 (1996).
3.Cho, S.Y.,Lee, J.H.,Bae, H.D., et al. Transglutaminase 2 inhibits apoptosis induced by calcium-overload through down-regulation of Bax. Exp. Mol. Med. 42(9), 639-650 (2010).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 523.6 |
| 分子式 | [C29H36N3O6]2 Ca •[C29H36N3O6]2 Mg |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
