VU0071063
货号:
21897-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 21897-1mg |
描述 | VU0071063 is a potent and selective activator of the inward-rectifier potassium channel (Kir) 6.2 and sulfonylurea receptor (SUR) 1 (EC50 = 7 µM using whole cell patch clamp electrophysiology).1 It is selective for SUR1-containing Kir6.1 or Kir6.2 channels over SUR2A, Kir2.1, Kir2.2, Kir2.3, Kir3.1/3/2, and voltage-gated potassium channel 2.1. VU0071063 inhibits glucose-stimulated calcium entry in isolated mouse pancreatic β-cells. |
性能供应商 | Cayman |
应用文献 |
1.Raphemot, R.,Swale, D.R.,Dadi, P.K., et al. Direct activation of β-cell KATP channels with a novel xanthine derivative. Mol. Pharmacol. 85(6), 858-865 (2014).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 326.4 |
分子式 | C18H22N4O2 |
CAS号 | 333415-38-6 |
稳定性 | ≥ 2 years |
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