货号 | 21820-1mg |
描述 | bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.1 Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.2bis-ANS has been used to label mechanically damaged neurons in acute brain slices.3 It also potently inhibits microtubule assembly.4,5 |
别名 | 4,4-Dianilino-1,1-binaphthyl-5,5-disulfonic Acid; |
供应商 | Cayman |
应用文献 | |
1.Hawe, A.,Sutter, M., and Jiskoot, W. Extrinsic fluorescent dyes as tools for protein characterization. Pharm. Res. 25(7), 1487-1499 (2008). 2.Bothra, A.,Bhattacharyya, A.,Mukhopadhyay, C., et al. A fluorescence spectroscopic and molecular dynamics study of bis-ANS/protein interaction. J. Biomol. Struct. Dyn. 15(5), 959-966 (1998). 3.Mozes, E.,Hunya, A.,Toth, A., et al. A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slices. Brain Res. Bull. 86(3-4), 217-221 (2011). 4.Horowitz, P.,Prasad, V., and Luduena, R.F. Bis(1,8-anilinonaphthalenesulfonate). A novel and potent inhibitor of microtubule assembly. J. Biol. Chem. 259(23), 14647-14650 (1984). 5.Mazumdar, M.,Parrack, P.K.,Mukhupadbhyay, K., et al. Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulin. Biochemistry 31(28), 6470-6474 (1992). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 672.9 |
分子式 | C32H22N2O6S2 • 2K |
CAS号 | 65664-81-5 |
稳定性 | ≥ 2 years |
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