MK-886
货号：
21753-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21753-1mg |
| 描述 | MK-886 is a potent, selective inhibitor of 5-lipoxygenase-activating protein (FLAP) that prevents 5-lipoxygenase activation in vivo and inhibits leukotriene biosynthesis in leukocytes with an IC50 of 2.5 nM.1 In human whole blood, leukotriene biosynthesis is inhibited by MK-886 with an IC50 of 1.1 µM. |
| 别名 | L-663,536; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Dixon, R.A.F.,Diehl, R.E.,Opas, E., et al. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343, 282-284 (1990).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 472.1 |
| 分子式 | C27H34ClNO2S |
| CAS号 | 118414-82-7 |
| 稳定性 | ≥ 2 years |
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