| 货号 | 21673-5mg |
| 描述 | 2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.1,2. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.3,4 |
| 别名 | 2,5-AHM;NSC 129241; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Tordoff, M.G.,Rafka, R.,DiNovi, M.J., et al. 2,5-anhydro-D-mannitol: a fructose analogue that increases food intake in rats. Am. J. Physiol. 254(1 Pt 2), R150 - R153 (1988). 2.Riquelme, P.T.,Wernette-Hammond, M.E.,Kneer, N.M., et al. Regulation of carbohydrate metabolism by 2,5-anhydro-D-mannitol. Proc. Natl. Acad. Sci. USA 80(14), 4301-4305 (1983). 3.Rawson, N.E.,Blum, H.,Osbakken, M.D., et al. Hepatic phosphate trapping, decreased ATP, and increased feeding after 2,5-anhydro-D-mannitol. Am. J. Physiol. 266(1 Pt 2), R112-R117 (1994). 4.Tordoff, M.G.,Rawson, N., and Friedman, M.I. 2,5-anhydro-D-mannitol acts in liver to initiate feeding. Am. J. Physiol. 261(2 Pt 2), R283-R188 (1991). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 164.2 |
| 分子式 | C6H12O5 |
| CAS号 | 41107-82-8 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |