5-N-Ethylcarboxamidoadenosine
货号：
21420-5mg 基本售价：
350.0 元 规格：
5 mg
产品信息
概述| 货号 | 21420-5mg |
| 描述 | 5-N-Ethylcarboxamidoadenosine (NECA) is an adenosine analog that acts as an agonist of adenosine receptors (Kis = 1,880, 6,660, and 3.5 nM for human adenosine subtypes A1, A2A, and A3, respectively).1 NECA is reported to act as a potent vasodilator and can inhibit platelet aggregation by increasing cAMP (EC50 = 3.1 µM).2,3 |
| 别名 | Adenosine 5-ethylcarboxamide;NECA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Volpini, R.,Dal ben, D.,Lambertucci, C., et al. N6-methoxy-2-alkynyladenosine derivatives as highly potent and selective ligands at the human A3 adenosine receptor. J. Med. Chem. 50(6), 1222-1230 (2007).
2.de Zwart, M.,Link, R.,von Frijtag Drabbe Künzel, J.K., et al. A functional screening of adenosine analogues at the adenosine A2B receptor: a search for potent agonists. Nucleosides Nucleotides 17(6), 969-985 (1998).
3.Cusack, N.J., and Hourani, S.M.O. 5-N-ethylcarboxamidoadenosine: A potent inhibitor of human platelet aggregation. Br. J. Pharmacol. 72(3), 443-447 (1981).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥99% |
| 计算分子量 | 308.3 |
| 分子式 | C12H16N6O4 |
| CAS号 | 35920-39-9 |
| 稳定性 | ≥ 1 year |
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