Mometasone Furoate
货号：
21365-25mg 基本售价：
350.0 元 规格：
25 mg
产品信息
概述| 货号 | 21365-25mg |
| 描述 | Mometasone furoate is a prodrug to mometasone, a glucocorticoid receptor agonist.1 Like other corticosteroids, mometasone furoate suppresses allergic, inflammatory, and immune responses in various experimental models.2 Mometasone furoate has been shown to decrease NF-κB activity in a farnesoid X receptor-dependent manner.3 |
| 别名 | SCH 32088; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Smith, C.L., and Kreutner, W. In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids. Arzneimittel-Forschung 48(9), 956-960 (1998).
2.Poachanukoon, O.,Koontongkaew, S.,Monthanapisut, P., et al. Mometasone furoate suppresses PMA-induced MUC-5AC and MUC-2 production in human airway epithelial cells. Tuberc. Repair. Dis. (Seoul) 80(1), 60-68 (2017).
3.Bijsmans, I.T.G.W.,Guercini, C.,Pittol, J.M.R., et al. The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression. Sci. Rep. 5(14086), 1-12 (2015).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 521.4 |
| 分子式 | C27H30Cl2O6 |
| CAS号 | 83919-23-7 |
| 稳定性 | ≥ 2 years |
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