EGT-1442
货号：
21359-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21359-1mg |
| 描述 | EGT-1442 is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 µM and 2 nM for human SGLT1 and SGLT2, respectively.1 It produces a stable urinary excretion of glucose in rats and dogs with ED50 values of 0.38 and 0.09 mg/kg, respectively, and reduces HbA(1c) and blood glucose in db/db mice in a concentration dependent manner. |
| 别名 | THR-1442; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhang, W.,Welihinda, A.,Mechanic, J., et al. EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacol. Res. 63(4), 284-293 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 464.9 |
| 分子式 | C24H29ClO7 |
| CAS号 | 1118567-05-7 |
| 稳定性 | ≥ 2 years |
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