NBD-556
货号：
21274-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21274-1mg |
| 描述 | NBD-556 is a small molecule CD4 mimetic that inhibits GP120 from interacting with CD4, preventing HIV-1 from entering CD4+ cells by binding to the GP120 exterior envelope glycoprotein.1 It inhibits infection of MT-2 cells by laboratory-adapted HIV-1 IIIB, MN, and V32 strains (IC50 = 6.5, 15.9, and 5.3 µM, respectively), an AZT-resistant (AZT-R) HIV-1 strain (IC50 = 58 µM), and various primary HIV-1 isolates (IC50s = 15-103 μM). |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhao, Q.,Ma, L.,Jiang, S., et al. Identification of N-phenyl-N-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology 339(2), 213-225 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 337.8 |
| 分子式 | C17H24ClN3O2 |
| CAS号 | 333353-44-9 |
| 稳定性 | ≥ 2 years |
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