Kukoamine B
货号：
21091-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21091-1mg |
| 描述 | Kukoamine B is a spermine alkaloid first isolated from a traditional Chinese herb L. chinense that inhibits both lipopolysaccharides (LPS) and oligodeoxynucleotides containing CpG motifs (CpG DNA).1 It is reported to inhibit proinflammatory signal transduction and cytokine expression induced by LPS and CpG DNA (Kds = 1.24 and 0.66 µM).1 LPS and CpG DNA are two well-recognized pathogen-associated molecular patterns (PAMPs) that play a role in triggering sepsis, thus sepsis may be attenuated by simultaneously neutralizing LPS and CpG DNA.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Liu, X.,Zheng, X.,Wang, N., et al. Kukoamine B, a novel dual inhibitor of LPS and CpG DNA, is a potential candidate for sepsis treatment. Br. J. Pharmacol. 162(6), 1274-1290 (2011).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 530.7 |
| 分子式 | C28H42N4O6 |
| CAS号 | 164991-67-7 |
| 稳定性 | ≥ 1 year |
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