| 货号 | 21061-25mg |
| 描述 | 5-methoxy Tryptophol (5-MTOH) is a natural indole that is produced by the pineal gland.1,2 It is a product of melatonin metabolism that may be biologically active.3,4 The levels of 5-MTOH in plasma vary in a diurnal pattern in rodents and humans.5,6 |
| 别名 | 5-MTOH; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Delvigs, P.,McIsaac, W.M. and Taborsky, R.G. The metabolism of 5-metholxytryptophol. J. Biol. Chem. 240(1), 348-350 (1965). 2.Mullen, P.E.,Leone, R.M.,Hooper, J., et al. Pineal 5-methoxy tryptophol in man. Psychoneuroendocrinology 4(2), 117-126 (1979). 3.Slominski, A.,Semak, I.,Pisarchik, A., et al. Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells. FEBS Lett. 511(1-3), 102-106 (2002). 4.Zisapel, N.,Egozi, Y. and Laudon, M. Circadian variations in the inhibition of dopamine release from adult and newborn rat hypothalamus by melatonin. Neuroendocrinology 40(2), 102-108 (1985). 5.Reddy, M.Y. and Jaqota, A. Melatonin has differential effects on age-induced stoichiometric changes in daily chronomics of serotonin metabolism in SCN of male Wistar rats. Biogerontology 16(3), 285-302 (2015). 6.Wurtman, R.J. and Ozaki, Y. Physiological control of melatonin synthesis and secretion: Mechanisms, generating rhythms in melatonin, methoxytryptophol, and arginine vasotocin levels and effects on the pineal of endogenous catecholamines, the estrous cycle, and environmental lighting. J. Neural Transm. Suppl. 13(13), 59-70 (1978). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 191.2 |
| 分子式 | C11H13NO2 |
| CAS号 | 712-09-4 |
| 稳定性 | ≥ 1 year |
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