BTB06584
货号：
21032-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 21032-1mg |
| 描述 | BTB06584 (BTB) is an inhibitor of mitochondrial F1Fo-ATP synthase (F1Fo-ATPase) that has no effect on mitochondrial membrane potential (ΔΨm) or oxygen consumption.1 It slows ATP consumption following inhibition of cellular respiration. BTB (100 μM) protects against ischemic cell death of HL-1 cells and rescues defective hemoglobin synthesis in pinotage (pnt) mutant zebrafish. BTB, in combination with ionizing radiation, increases apoptosis of A549 cells.2 |
| 别名 | BTB; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ivanes, F.,Faccenda, D.,Gatliff, J., et al. The compound BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase. Br. J. Pharmacol. 171(18), 4193-4206 (2014).
2.Wang, Y.,Hou, Q.,Xiao, G., et al. Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549). Oncotarget (2017).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 417.8 |
| 分子式 | C19H12ClNO6S |
| CAS号 | 219793-45-0 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
