Mepyramine (maleate)
货号：
20978-1g 基本售价：
350.0 元 规格：
1 g
产品信息
概述| 货号 | 20978-1g |
| 描述 | Mepyramine is a first generation antihistamine that acts as an inverse agonist at the histamine H1 receptor. It is reported to bind with high affinity to a Gq/11 protein-coupled form of the receptor and to promote a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling of the endogenously expressed receptor, as well as to reduce G protein availability for other non-related receptors associated with this signaling pathway.1 Mepyramine has been shown to inhibit histamine-induced inositol phosphate production with a log EC50 value of -7.94.1 |
| 别名 | NSC 3604;Pyrilamine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fitzsimons, C.P.,Monczor, F.,Fernández, N., et al. Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein. J. Biol. Chem. 279(33), 34431-34439 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 401.5 |
| 分子式 | C17H23N3O • C4H4O4 |
| CAS号 | 59-33-6 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
