货号 | 20959-1mg |
描述 | 1-Oleoyl-2-hydroxy-sn-glycero-3-PC is an unsaturated 18:1 lysophosphatidylcholine formed in plasma by lecithin:cholesterol acyltransferase (LCAT).1,2 Lysophosphatidylcholines play a role in lipid signaling to regulate gene transcription, mitogenesis, monocyte chemotaxis, smooth muscle relaxation, and platelet activation.3,4,5 |
别名 | 18:1 Lyso-PC;1-Oleoyl-2-hydroxy-sn-glycero-3-Phosphocholine; |
供应商 | Cayman |
应用文献 | |
1.Soupene, E.,Fyrst, H. and Kuypers, F.A. Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes. Proceedings of the National Academy of Sciences of the United States of America 105(1), 88-93 (2008). 2.Florin-Christensen, J.,Narvaez-Vasquez, J.,Florin-Christensen, M., et al. A method for distinguishing 1-acyl from 2-acyl lysophosphatidylcholines generated in biological systems. Analytical Biochemistry 276, 13-17 (1999). 3.Yuan, Y.,Schoenwaelder, S.M.,Salem, H.H., et al. The bioactive phospholipid, lysophosphatidylcholine, induces cellular effects via G-protein-dependent activation of adenylyl cyclase. The Journal of Biological Chemisty 271, 27090-27098 (1996). 4.Lundbæk, J.A. and Andersen, O.S. Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers. Journal of General Physiology 104, 645-673 (1994). 5.Kabarowski, J.H.S.,Zhu, K.,Le, L.Q., et al. Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. Science 293, 702-705 (2001). | |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥95% |
计算分子量 | 521.7 |
分子式 | C26H52NO7P |
CAS号 | 19420-56-5 |
稳定性 | ≥ 1 year |
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