| 货号 | 20948-250mg |
| 描述 | 4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease.1,2,3 Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.4 |
| 别名 | 4-MU-GLU;4-MU-β-Gluc;4-MUG;MU-GLU; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hernández-Guzmán, A.,Flores-Martínez, A.,Ponce-Noyola, P., et al. Purification and characterization of an extracellular β-glucosidase from Sporothrix schenckii. FEBS Open Bio. 6(11), 1067-1077 (2016). 2.Kwapiszewski, R.,Skolimowski, M.,Ziółkowska, K., et al. A microfluidic device with fluorimetric detection for intracellular components analysis. Biomed Microdevices 13(3), 431-440 (2011). 3.Shanmuganathan, M.K. and Britz-McKibbin, P. Inhibitor screening of pharmacological chaperones for lysosomal β-glucocerebrosidase by capillary electrophoresis. Anal. Bioanal. Chem. 399(8), 2843-2853 (2011). 4.Zhi, H.,Wang, J.,Wang, S., et al. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule. J. Spectrosc. 2013, 1-9 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 338.3 |
| 分子式 | C16H18O8 |
| CAS号 | 18997-57-4 |
| 稳定性 | ≥ 2 years |
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