Aminoglutethimide
货号：
20947-1g 基本售价：
350.0 元 规格：
1 g
产品信息
概述| 货号 | 20947-1g |
| 描述 | Aminoglutethimide is an aromatase inhibitor (IC50 = 7.5 µM).1 Aromatase inhibitors, including aminoglutethimide, inhibit estrogen synthesis via aromatase, suppressing estrogen levels in post-menopausal women. Formulations containing aromatase inhibitors have been used to treat estrogen receptor-positive breast cancer in post-menopausal women.2,3 |
| 别名 | DL-Aminoglutethimide;NSC 330915; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Campbell, D.R. and Kurzer, M.S. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. Journal of Steroid Biochemistry and Molecular Biology 46, 381-388 (1993).
2.Santen, R.J. and Harvey, H.A. Use of aromatase inhibitors in breast carcinoma. Endocr.-Relat.Cancer 6, 75-92 (1999).
3.Smith, I.E. and Dowsett, M. Aromatase inhibitors in breast cancer. New England Journal of Medicine 348, 2431-2442 (2003).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 232.3 |
| 分子式 | C13H16N2O2 |
| CAS号 | 125-84-8 |
| 稳定性 | ≥ 2 years |
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