| 货号 | 20945-5mg |
| 描述 | NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals it is predominantly produced by the pentose phosphate pathway, but it is also generated by key mitochondrial enzymes. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species.1,2,3 It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation.4 |
| 别名 | Nicotinamide adenine dinucleotide phosphate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Sumimoto, H. Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS Journal 275, 3249-3277 (2008). 2.Sutherland, M.W.,Nelson, J.,Harrison, G., et al. Effects of t-butyl hydroperoxide on NADPH, glutathione, and the respiratory burst of rat alveolar machrophages. Arch. Biochem. Biophys. 243, 325-331 (1985). 3.Nauseef, W.M. Biological roles for the NOX family NADPH oxidases. J. Biol. Chem. 283(25), 16961-16965 (2008). 4.Tserng, K.Y. and Jin, S.J. NADPH-dependent reductive metabolism of cis-5 unsaturated fatty acids. A revised pathway for the β-oxidation of oleic acid. J. Biol. Chem. 266, 11614-11620 (1990). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 1142.1 |
| 分子式 | C21H30N7O17P3 • 4C6H13N |
| CAS号 | 100929-71-3 |
| 稳定性 | ≥ 2 years |
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