Brassinin
货号：
20922-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 20922-1mg |
| 描述 | Brassinin (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.1,2 Brassinin suppresses constitutive and IL-6-induced STAT3 activation in vitro and attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3).3 Brassinin also induces apoptosis in PC3 cells through suppression of PI3K, Akt, mTOR, and S6K1.1 |
| 别名 | BSN; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, S.-M.,Park, J.H.,Kim, K.D., et al. Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades. Phytother. Res. 28(3), 423-431 (2014).
2.Pedras, M.S.,Montaut, S. and Suchy, M. Phytoalexins from the crucifer rutabaga: Structures, syntheses, biosyntheses, and antifungal activity. J. Org. Chem. 69(13), 4471-4476 (2004).
3.Lee, J.H.,Kim, C.,Sethi, G., et al. Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel. Oncotarget 6(8), 6386-6405 (2015).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 236.4 |
| 分子式 | C11H12N2S2 |
| CAS号 | 105748-59-2 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
