Diallyl Sulfide
货号：
20894-25g 基本售价：
350.0 元 规格：
25 g
产品信息
概述| 货号 | 20894-25g |
| 描述 | Diallyl sulfide is a thioether found in garlic that can modulate the cytochrome P450 drug metabolizing system, activate the constitutive androstane receptor to regulate multidrug resistance-associated proteins, and upregulate the expression of detoxifying enzymes.1,2 Garlic-derived organosulfides such as diallyl sulfide have been shown to be highly protective from chemically-induced carcinogenesis in animals.3 |
| 别名 | Allyl Sulfide;DAS;NSC 20947; |
| 是否危险品 | 是 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Maher, J.M.,Cheng, X.,Slitt, A.L., et al. Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metabolism and Disposition 33(7), 956-962 (2005).
2.Magesh, S.,Chen, Y. and Hu, L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents. Medicinal Research Reviews 32(4), 687-726 (2012).
3.Xiao, D.,Choi, S.,Johnson, D.E., et al. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene 23, 5594-5606 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 114.2 |
| 分子式 | C6H10S |
| CAS号 | 592-88-1 |
| 稳定性 | ≥ 2 years |
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