2-Iminobiotin
货号：
20812-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 20812-10mg |
| 描述 | 2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Kis = 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively).1 It also provides gender-specific neuroprotection against hypoxia-ischemia in neonatal rats by an NO-independent mechanism.2 2-Iminobiotin has also been used to capture membrane-bound proteins through biotin-avidin interactions.3 |
| 别名 | Guanidinobiotin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sup, S.J.,Green, B.G. and Grant, S.K. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem. Biophys. Res. Commun. 204(2), (1994).
2.Nijboer, C.H.A.,Groenendaal, F.,Kavelaars, A., et al. Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway. Journal of Cerebral Blood Flow and Metabolism 27, 282-292 (2007).
3.Orr, G.A. The use of the 2-iminobiotin-avidin interaction for the selective retrieval of labeled plasma membrane components. J. Biol. Chem. 256(2), 761-766 (1981).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 243.3 |
| 分子式 | C10H17N3O2S |
| CAS号 | 13395-35-2 |
| 稳定性 | ≥ 2 years |
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