Chlorprothixene (hydrochloride)
货号：
20772-1g 基本售价：
350.0 元 规格：
1 g
产品信息
概述| 货号 | 20772-1g |
| 描述 | Chlorprothixene is a thioxanthine antipsychotic that functions by antagonizing dopamine D2receptors.1 It can block a subset of GABAA receptors in rat cortex that is also blocked by clozapine (Item No. 12059).2 It has also been shown to be effective against P. falciparum growth with an EC50 value of 1.7 µM.3 |
| 别名 | cis-Chlorprothixene;NSC 169899; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Froimowitz, M. and Cody, V. Biologically active conformers of phenothiazines and thioxanthenes. Further evidence for a ligand model of dopamine D2 receptor antagonists. J. Med. Chem. 36(15), 2219-2227 (1993).
2.Squires, R.F. and Saederup, E. Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same “core” fraction of GABAA receptors. Neurochem. Res. 23(10), 1283-1290 (1998).
3.Weisman, J.L.,Liou, A.P.,Shelat, A.A., et al. Searching for new antimalarial therapeutics amongst known drugs. Chem.Biol.Drug Des. 67(6), 409-416 (2006).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 352.3 |
| 分子式 | C18H18ClNS • HCl |
| CAS号 | 6469-93-8 |
| 稳定性 | ≥ 2 years |
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