Loxapine (succinate)
货号：
20760-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 20760-50mg |
| 描述 | Loxapine is an atypical antipsychotic drug that displays high affinity for histamine, 5-HT, dopamine, and α1-adrenergic receptors (Ki values are 7, 7.7, 9.5, 12, and 31 nM for H1, 5-HT2A, 5-HT2C, D2, and α1A, respectively).1,2 It reduces agitation associated with schizophrenia or bipolar disorder.3 |
| 别名 | CL 71,563; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Seeman, P.,Corbett, R. and Van Tol, H.H. Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors. Neuropsychopharmacology 16(2), 93-110 (1997).
2.Kroeze, W.K.,Hufeisen, S.J.,Popadak, B.A., et al. H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 28(3), 519-526 (2003).
3.Zeller, S.L. and Citrome, L. Managing agitation qssociated with schizophrenia and bipolar disorder in the emergency setting. West J. Emerg. Med. 17(2), 165-172 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 445.9 |
| 分子式 | C18H18ClN3O • C4H6O4 |
| CAS号 | 27833-64-3 |
| 稳定性 | ≥ 2 years |
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