| 货号 | 20703-1mg |
| 描述 | Fluticasone propionate is a synthetic corticosteroid that potently activates the glucocorticoid receptor (Kd = 0.5 nM).1 It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis, and other airway diseases.2,3,4 |
| 别名 | Fluticasone 17-propionate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Smith, C.L. and Kreutner, W. In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids. Arzneimittel-Forschung 48(9), 956-960 (1998). 2.Sastre, J. and Mosges, R. Local and systemic safety of intranasal corticosteroids. J. Investig. Allergol. Clin. Immunol. 22(1), 1-12 (2012). 3.Prenner, B.M. A review of the clinical efficacy and safety of MP-AzeFlu, a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate, in clinical studies conducted during different allergy seasons in the US. J. Asthma Allergy 9, 135-143 (2016). 4.González-Cervera, J. and Lucendo, A.J. Eosinophilic esophagitis: An evidence-based approach to therapy. J. Investig. Allergol. Clin. Immunol. 26(1), 8-18 (2016). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 500.6 |
| 分子式 | C25H31F3O5S |
| CAS号 | 80474-14-2 |
| 稳定性 | ≥ 2 years |
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