4-bromo-Resveratrol
货号：
20541-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 20541-1mg |
| 描述 | 4’-bromo-Resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3).1 It is a brominated derivative of resveratrol, a polyphenol found in red wine, which activates SIRT1 and inhibits SIRT3. The use of 4’-bromo-resveratrol in an SIRT3 crystal binding study revealed two compound binding sites which, combined with homology modeling, suggested that the second site may account for the paradoxical activation of SIRT1 by unmodified resveratrol.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Nguyen, G.T.T.,Gertz, M. and Steegborn, C. Crystal structures of Sirt3 complexes with 4-bromo-resveratrol reveal binding sites and inhibition mechanism. Chem. Biol. 20(11), 1375-1385 (2013).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 291.1 |
| 分子式 | C14H11BrO2 |
| CAS号 | 1224713-90-9 |
| 稳定性 | ≥ 2 years |
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