| 货号 | 20523-1mg |
| 描述 | Ertapenem is a long-acting, broad-spectrum antibiotic that is in the β-lactam subclass known as carbapenems.1,2,3 It inhibits the synthesis of bacterial cell walls by attaching to penicillin-binding proteins. Ertapenem is effective against Gram-positive and Gram-negative bacteria.4,5 Resistance to ertapenem results from the expression of certain β-lactamases and carbapenemases.6 |
| 别名 | L-749; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Mandell, L. Doripenem: A new carbapenem in the treatment of nosocomial infection. Clinical Infectious Diseases 49, S1-S3 (2009). 2.Paterson, D.L. and DePestel, D.D. Doripenem. Clinical Infectious Diseases 49, 291-298 (2009). 3.Papp-Wallace, K.M.,Endimiani, A.,Taracila, M.A., et al. Carbapenems: Past, present, and future. Antimicrobial Agents and Chemotherapy 55(11), 4943-4960 (2011). 4.Shah, P.M. and Isaacs, R.D. Ertapenem, the first fo a new group of carbapenems. Journal of Antimicrobial Chemotherapy 52, 538-542 (2003). 5.Wexler, H.M. In vitro activity of ertapenem: Review of recent studies. Journal of Antimicrobial Chemotherapy 53(Suppl. S2), ii11-ii21 (2004). 6.Jeon, J.H.,Lee, J.H.,Lee, J.J., et al. Structural basis for carbapenem-hydrolyzing mechanisms of carbapenemases conferring antibiotic resistance. Int. J. Mol. Sci. 16, 9654-9692 (2015). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 519.5 |
| 分子式 | C22H23N3O7S • 2Na |
| CAS号 | 153832-38-3 |
| 稳定性 | ≥ 2 years |
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