3-methoxy Tyramine (hydrochloride)
货号：
20511-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 20511-50mg |
| 描述 | 3-methoxy Tyramine (hydrochloride) is a natural metabolite of dopamine, produced by catechol-O-methyltransferase (COMT). It is a weak agonist of trace amine-associated receptor 1 (EC50 = 1.7 µM).1 3-methoxy Tyramine (hydrochloride) levels are assessed to monitor COMT activity in Parkinson’s disease.2 Elevated 3-methoxy Tyramine (hydrochloride) levels may also indicate abnormal catecholamine synthesis that occurs in certain neuroendocrine tumors.3 |
| 别名 | 3-Methoxy-4-hydroxyphenethylamine;3-Methoxy-p-hydroxyphenethylamine;3-O-methyl Dopamine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wainscott, D.B.,Little, S.P.,Yin, T., et al. Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1. Journal of Pharmacology and Experimental Therapeutics 320(1), 475-485 (2007).
2.Espinoza, S.,Managó, F.,Leo, D., et al. Role of catechol-O-methyltransferase (COMT)-dependent processes in Parkinson’s disease and L-DOPA treatment. CNS Neurol.Disord.Drug Targets 11(3), 251-263 (2012).
3.van Berkel, A.,Lenders, J.W., and Timmers, H.J. Diagnosis of endocrine disease: Biochemical diagnosis of phaeochromocytoma and paraganglioma. Eur.J.Endocrinol. 170(3), R910-R119 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 203.7 |
| 分子式 | C9H13NO2 • HCl |
| CAS号 | 1477-68-5 |
| 稳定性 | ≥ 2 years |
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