| 货号 | 20341-1g |
| 描述 | Nitrofen is an herbicide with potent teratogenic activity in rats and mice.1 It induces bilateral pulmonary hypoplasia and an immature lung architecture in fetal rats and mice, which is used to model human congenital diaphragmatic hernia.2,3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Manson, J.M. Mechanism of nitrofen teratogenesis. Environ. Health Perspect. 70, 137-147 (1986). 2.Allan, D.W., and Greer, J.J. Pathogenesis of nitrofen-induced congenital diaphragmatic hernia in fetal rats. J. Appl. Physiol. 83(2), 338-347 (1997). 3.Guilbert, T.W.,Gebb, S.A., and Shannon, J.M. Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development. Am. J. Physiol Lung Cell. Mol. Physiol. 279(6), L1159-L1171 (2000). 4.Pereira-Terra, P.,Moura, R.S.,Nogueira-Silva, C., et al. Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung development. J. Physiol. 593(15), 3301-3311 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 284.1 |
| 分子式 | C12H7Cl2NO3 |
| CAS号 | 1836-75-5 |
| 稳定性 | ≥ 2 years |
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