Delafloxacin
货号：
20314-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 20314-1mg |
| 描述 | Delafloxacin is a fluoroquinolone antibiotic that demonstrates extremely high potency against a wide range of bacteria in vitro, including levofloxacin-resistant strains of S. pneumoniae and methicillin-resistant S. aureus.1,2 It targets both DNA gyrase and topoisomerase IV. Delafloxacin has an anionic structure, which enhances its potency in acidic environments (e.g., phagolysosome, inflammatory cells) and in skin and soft tissue infections.3 |
| 别名 | ABT-492;RX-3341; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Goldstein, E.J.C.,Citron, D.M.,Merriam, C.V., et al. In vitro activities of ABT-492, a new fluoroquinolone, against 155 aerobic and 171 anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. Antimicrob. Agents Chemother. 47(9), 3008-3011 (2003).
2.Nilius, A.M.,Shen, L.L.,Hensey-Rudloff, D., et al. In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone. Antimicrob. Agents Chemother. 47(10), 3260-3269 (2003).
3.Kocsis, B.,Domokos, J., and Szabo, D. Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin. Ann. Clin. Microbiol. Antimicrob. 15(1), 34 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | 0.98 |
| 计算分子量 | 440.8 |
| 分子式 | C18H12ClF3N4O4 |
| CAS号 | 189279-58-1 |
| 稳定性 | ≥ 2 years |
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