Rotigotine
货号：
20246-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 20246-1mg |
| 描述 | Rotigotine is a non-selective dopamine receptor agonist with pEC50 values of 9.6, 10.4, 8.2, 7.7, and 7.7 for D1, D2, D3, D4, and D5, respectively.1 It demonstrates a high-affinity for D1, D2, and D3 with lesser affinity for D4 and D5 receptor subtypes.1 This binding profile is similar to that of apomorphine (Item No. 16094) and pergolide but differentiated from that of pramipexole (Item No. 11981) and ropinirole, which have a more narrow profile of receptor specificity.1 Each of these agonists demonstrates anti-Parkinsonian effects in animal and clinical models through their ability to directly activate dopamine receptors.1 |
| 别名 | N-0923;SPM 962; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wood, M.,Dubois, V.,Scheller, D., et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br. J. Pharmacol. 172(4), 1124-1135 (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 315.5 |
| 分子式 | C19H25NOS |
| CAS号 | 99755-59-6 |
| 稳定性 | ≥ 2 years |
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