PCI 24781
货号:
20059-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 20059-1mg |
描述 | PCI 24781 is an HDAC inhibitor that predominantly targets HDAC1 with a Ki value of 7 nM.1 It inhibits HDAC2, HDAC3/SMRT, HDAC6, HDAC8, and HDAC10 with Ki values of 19, 8.2, 17, 280, and 24 nM, respectively.1 PCI 24781 can prevent the growth of tumor cells in vitro, inducing apoptosis, as well as in mice harboring HCT116 or DLD-1 colon tumor xenografts.1 |
别名 | CRA-024781;CRA-24781; |
性能供应商 | Cayman |
应用文献 |
1.Buggy, J.J.,Cao, Z.A.,Bass, K.E., et al. CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo. Mol. Cancer Ther. 5(5), 1309-1317 (2006).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 397.4 |
分子式 | C21H23N3O5 |
CAS号 | 783355-60-2 |
稳定性 | ≥ 2 years |
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