CeMMEC1
货号：
19956-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 19956-500ug |
| 描述 | CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 µM; IC50 = 0.9 µM).1 It does not bind to either the first or second bromodomain of BRD4.1 This compound synergizes with (+)-JQ1 (Item No. 11187) to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sdelci, S.,Lardeau, C.H.,Tallant, C., et al. Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Nature Chemical Biology 12(7), 504-510 (2016).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 336.3 |
| 分子式 | C19H16N2O4 |
| CAS号 | 440662-09-9 |
| 稳定性 | ≥ 2 years |
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