Daprodustat
货号：
19915-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19915-1mg |
| 描述 | Daprodustat is an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase that increases HIF stability and action. It is orally bioavailable, induces an effective erythropoietin (EPO) response, and stimulates non-EPO mechanisms of erythropoiesis in animal models. Daprodustat and related HIF prolyl hydroxylase inhibitors are in clinical trials for the treatment of anemia associated with chronic kidney disease.1,2 |
| 别名 | GSK1278863; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Brigandi, R.A.,Johnson, B.,Oei, C., et al. A novel hypoxia-inducible factor-prolyl hydroxylase inhibitor (GSK1278863) for anemia in CKD: A 28-day, phase 2A randomized trial. Am.J.Kidney Dis. 67(6), 861-871 (2016).
2.Schmid, H., and Jelkmann, W. Investigational therapies for renal disease-induced anemia. Expert.Opin.Investig.Drugs 25(8), 901-916 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 393.4 |
| 分子式 | C19H27N3O6 |
| CAS号 | 960539-70-2 |
| 稳定性 | ≥ 2 years |
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