Acalabrutinib
货号：
19899-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19899-1mg |
| 描述 | Acalabrutinib is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells.1 In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Item No. 16274) for inhibiting BTK and did not inhibit EGFR, Itk, or Txk signaling.1 |
| 别名 | ACP-196; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Burd, J.C.,Harrington, B.,OBrien, S., et al. Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia. N. Engl. J. Med. 374(4), 323-332 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 465.5 |
| 分子式 | C26H23N7O2 |
| CAS号 | 1420477-60-6 |
| 稳定性 | ≥ 2 years |
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