| 货号 | 19867-10mg |
| 描述 | Rhapontin is a natural stilbenoid glycoside first isolated from rhubarb rhizomes. It is converted by glucosidases to rhapontigenin (Item No. 13293), a resveratrol analog with antioxidant and anti-cancer activity.1,2,3 Rhapontigenin derived enzymatically from rhapontin has also been found to have antibiotic activity as well as inhibit melanin synthesis.4,5 |
| 别名 | NSC 43321;Rhaponticin;trans-Rhapontin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Chun, Y.J.,Ryu, S.Y.,Jeong, T.C., et al. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin. Drug Metabolism and Disposition 29(4), 389-393 (2001). 2.Roupe, K.A.,Helms, G.L.,Halls, S.C., et al. Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: Applications to metabolism, pharmacokinetics and anti-cancer studies. Journal of Pharmacy & Pharmaceutical Sciences 8(3), 374-386 (2005). 3.Roberti, M.,Pizzirani, D.,Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. Journal of Medicinal Chemistry 46, 3546-3554 (2003). 4.Kim, J.-K.,Kim, N., and Lim, Y.-H. Evaluation of the antibacterial activity of rhapontigenin produced from rhapontin by biotransformation against Propionibacterium acnes. J.Microbiol.Biotechnol. 20(1), 82-87 (2010). 5.Lee, H.-S.,Kim, J.-K.,Park, K.-T., et al. Rhapontigenin converted from rhapontin purified from Rheum undulatum enhances the inhibition of melanin synthesis. Biosci.Biotechnol.Biochem. 76(12), 2307-2309 (2012). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 420.4 |
| 分子式 | C21H24O9 |
| CAS号 | 155-58-8 |
| 稳定性 | ≥ 2 years |
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