| 货号 | 19864-500mg |
| 描述 | Pregnenolone is a natural steroid hormone that serves as a precursor for a wide range of steroids, including mineralocorticoids, glucocorticoids, androgens, and estrogens.1 Pregnenolone sulfate modulates NMDA receptor responses to exogenously applied glutamate and stimulates transient receptor potential melastatin 3 (TRPM3).2,3,4 |
| 别名 | NSC 1616;NSC 18158;3β-hydroxy-5-Pregnen-20-one;Δ5-Pregnenolone; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Akhtar, M.K.,Kelly, S.L., and Kaderbhai, M.A. Cytochrome b5 modulation of 17α hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis. J. Endocrinol. 187(2), 267-274 (2005). 2.Sedláček, M.,Kořínek, M.,Petrovič, M., et al. Neurosteroid modulation of ionotropic glutamate receptors and excitatory synaptic transmission. Physiol. Res. 57(Suppl 3), S49-S57 (2008). 3.Smith, C.C.,Gibbs, T.T., and Farb, D.H. Pregnenolone sulfate as a modulator of synaptic plasticity. Psychopharmacology (Berl) 231(17), 3537-3556 (2014). 4.Thiel, G.,Müller, I., and Rössler, O.G. Signal transduction via TRPM3 channels in pancreatic β-cells. J. Mol. Endocrinol. 50(3), R75-R83 (2013). | |
| 运输条件 | Ambient in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 316.5 |
| 分子式 | C21H32O2 |
| CAS号 | 145-13-1 |
| 稳定性 | ≥ 2 years |
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