Physcion
货号:
19863-5mg 基本售价:
350.0 元 规格:
5 mg
产品信息
概述货号 | 19863-5mg |
描述 | Physcion is a natural anthraquinone. It has been reported to have laxative and anti-inflammatory actions, inhibit kinases and tyrosinase, and have cytotoxicity against cancer cells.1 Physcion inhibits 6-phosphogluconate dehydrogenase (IC50 = 38.5 µM), decreasing lipogenesis and RNA biosynthesis in cancer cells, leading to reduced cell proliferation and tumor growth in mice.2 |
别名 | 6-O-methyl Emodin;NSC 251670; |
性能供应商 | Cayman |
应用文献 |
1.Chien, S.-C.,Wu, Y.-C., and Chen, Z.-W. Naturally occurring anthraquinones: Chemistry and therapeutic potential in autoimmune diabetes.. Evid. Based Complement. Altnernat. Med. 2015:35757, (2015). 2.Lin, R.,Elf, S.,Shan, C., et al. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat. Cell Biol. 17(11), 1484-1496 (2015).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 284.3 |
分子式 | C16H12O5 |
CAS号 | 521-61-9 |
稳定性 | ≥ 2 years |
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