BRD4884
货号:
19834-500ug 基本售价:
350.0 元 规格:
500 ug
产品信息
概述货号 | 19834-500ug |
描述 | BRD4884 is an HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively.1 It possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min versus 20 min).1 BRD4884 crosses the blood brain barrier and has been evaluated in CK-p25 mice, a mouse model of neurodegeneration.1 |
性能供应商 | Cayman |
应用文献 |
1.Wagner, F.F.,Zhang, Y.-L.,Fass, D.M., et al. Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers. Chem.Sci. 6(1), 804-815 (2015).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 314.4 |
分子式 | C18H19FN2O2 |
CAS号 | 1404559-91-6 |
稳定性 | ≥ 2 years |
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