MIM1
货号：
19832-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19832-1mg |
| 描述 | MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein with a role in cancer. It selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains (IC50 = 4.7 µM).1 MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Cohen, N.A.,Stewart, M.L.,Gavathiotis, E., et al. A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival. Chem. Biol. 19(9), 1175-1185 (2012).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 347.4 |
| 分子式 | C17H21N3O3S |
| CAS号 | 509102-00-5 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
