SCH 58261
货号：
19676-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19676-1mg |
| 描述 | SCH 58261 is a competitive antagonist of the adenosine A2A receptor (Kis = 2.3 and 2.0 nM in rat and bovine brain, respectively).1 It is selective for the A2A subtype, displaying an A1/A2A selectivity ratio of 50-100-fold and does not interact with A2B or A3receptors.1 SCH 58261 has been used to improve 6-hydroxy dopamine-induced motor deficits in a rat model of Parkinson’s disease.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zocchi, C.,Ongini, E.,Ferrara, S., et al. Binding of the radioligand [3H]-SCH 58261, a new non-xanthine A2A adenosine receptor antagonist, to rat striatal membranes. Br. J. Pharmacol. 117(7), 1381-1386 (1996).
2.Reyhani-Rad, S., and Mahmoudi, J. Effect of adenosine A2A receptor antagonists on motor disorders induced by 6-hydroxydopamine in rat. Acta. Cir. Bras. 31(2), 133-137 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 345.4 |
| 分子式 | C18H15N7O |
| CAS号 | 160098-96-4 |
| 稳定性 | ≥ 2 years |
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