HM61713
货号：
19481-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19481-1mg |
| 描述 | HM61713 is a third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that inhibits both EGFR activating and T790M resistance mutations, while sparing wild-type EGFR.1,2 It has been investigated in Phase II clinical trials in patients with EGFR T790M mutation-positive non-small cell lung cancer (NSCLC), who developed resistance to earlier generations of EGFR tyrosine kinase inhibitor therapy.2 |
| 别名 | BI-1482694;Olmutinib; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Liao, B.C.,Lin, C.C., and Yang, J.C. Second and third-generation epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer. Curr.Opin.Oncol. 27(2), 94-101 (2015).
2.Stinchcombe, T.E. Targeted therapies for treatment of non-small cell lung cancer--recent advances and future perspectives. Int.J.Cancer 138(11), 2549-2561 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 486.6 |
| 分子式 | C26H26N6O2S |
| CAS号 | 1353550-13-6 |
| 稳定性 | ≥ 2 years |
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