| 货号 | 19461-1g |
| 描述 | Griseofulvin is a natural bacterial product used, in certain formulations, as an oral antibiotic for fungal infections of the skin.1 It alters microtubule dynamics, resulting in metaphase arrest.2 Antimicrotubule agents, including griseofulvin, have potential applications in cancer therapy, particularly when combined with other chemotherapeutic compounds.3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Flint, A.,Forsey, R.R., and Usher, B. Griseofulvin, a new oral antibiotic for the treatment of fungous infections of the skin. Can.Med.Assoc.J. 81(3), 173-175 (1959). 2.Roobol, A.,Gull, K., and Pogson, C.I. Griseofulvin-induced aggregation of microtubule protein. Biochemistry Journal 167(1), 39-43 (1977). 3.Singh, P.,Rathinasamy, K.,Mohan, R., et al. Microtubule assembly dynamics: An attractive target for anticancer drugs. IUBMB Life 60(6), 368-375 (2008). 4.Coyne, C.P.,Jones, T., and Bear, R. Anti-neoplastic cytotoxicity of gemcitabine-(C4-amide)-[anti-HER2/neu] in combination with griseofulvin against chemotherapeutic-resistant mammary adenocarcinoma (SKBr-3). Med.Chem.(Los Angeles) 3(2), 210-223 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 352.8 |
| 分子式 | C17H17CIO6 |
| CAS号 | 126-07-8 |
| 稳定性 | ≥ 2 years |
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