Lenvatinib
货号：
19375-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19375-1mg |
| 描述 | Lenvatinib is a potent inhibitor of VEGF-R2 and VEGF-R3 kinase activities with IC50 values of 4.0 and 5.2 nM, respectively.1,2. It is slightly less potent against the related receptor kinases VEGF-R1, FGF-R1, PGDFR3β and Kit (IC50 values of 22, 46, 39, and 100 nM, respectively). It is orally active, inhibiting H136 cell tumor growth in mice at 30 mg/kg.1 |
| 别名 | E-7080;ER-203492-00; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Matsui, J.,Yamamaoto, Y.,Funahashi, Y., et al. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int. J. Cancer 122(3), 664-671 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 426.9 |
| 分子式 | C21H19ClN4O4 |
| CAS号 | 417716-92-8 |
| 稳定性 | ≥ 2 years |
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