货号 | 19196-10g |
描述 | Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol.1 It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities.2 Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 µg/ml), proteasome activity, and cancer cell proliferation.3,4 Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro.5 |
别名 | 3,5-dimethyl ether Gallic Acid;3,5-dimethoxy-4-hydroxy Benzoic Acid;NSC 2129; |
是否危险品 | 是 |
供应商 | Cayman |
应用文献 | |
1.Hara, H.,Masai, E.,Katayama, Y., et al. The 4-oxalomesaconate hydratase gene, involved in the protocatechuate 4,5-cleavage pathway, is essential to vanillate and syringate degradation in Sphingomonas paucimobilis SYK-6. Journal of Bacteriology 182(24), 6950-6957 (2000). 2.Cotoras, M.,Vivanco, H.,Melo, R., et al. In vitro and in vivo evaluation of the antioxidant and prooxidant activity of phenolic compounds obtained from grape (Vitis vinifera) pomace. Molecules 19(12), 21154-21167 (2014). 3.Wei, X.,Chen, D.,Yi, Y., et al. Syringic acid extracted from Herba dendrobii prevents diabetic cataract pathogenesis by inhibiting aldose reductase activity. Evidence-Based Complementary and alternative Medicine 2012:426537, (2012). 4.Orabi, K.Y.,Abazar, M.S.,El Sayed, K.A., et al. Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors. Cancer Cell Int. 13(1), (2013). 5.Oboh, G.,Isaac, A.T.,Akinyemi, A.J., et al. Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside induced lipid peroxidation in rats pancreas by phenolic extracts of avocado pear leaves and fruit. Int.J.Biomed.Sci. 10(3), 208-216 (2014). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 198.2 |
分子式 | C9H10O5 |
CAS号 | 530-57-4 |
稳定性 | ≥ 2 years |
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