Xanthurenic Acid
货号：
19191-500mg 基本售价：
350.0 元 规格：
500 mg
产品信息
概述| 货号 | 19191-500mg |
| 描述 | Xanthurenic acid is formed upon tryptophan degradation by indoleamine 2,3-dioxygenase. It has been shown to be an endogenous Group II metabotropic glutamate receptor (mGluR2 and mGluR3) agonist and is implicated in the pathophysiology of schizophrenia.1,2 Xanthurenic acid has also been identified as an inducer of gametogenesis of P. falciparum, the parasite that causes malaria, and thus, is a target for the development of new methods to interrupt the transmission of malaria.3 |
| 别名 | NSC 401570;Xanthurenate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Copeland, C.S.,Neale, S.A., and Salt, T.E. Actions of xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology 66, 133-142 (2013).
2.Fazio, F.,Lionetto, L.,Curto, M., et al. Xanthurenic acid activates mGlu2/3 metabotropic glutamate receptors and is a potential trait marker for schizophrenia. Sci.Rep. 5:17799, (2015).
3.Billker, O.,Lindo, V.,Panico, M., et al. Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito. Nature 392, 289-269 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 205.2 |
| 分子式 | C10H7NO4 |
| CAS号 | 59-00-7 |
| 稳定性 | ≥ 2 years |
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