CCT241533 (hydrochloride)
货号：
19178-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 19178-500ug |
| 描述 | CCT241533 is a selective inhibitor of checkpoint kinase 2 (Chk2; IC50 = 3 nM).1 In human cancer cell lines, CCT241533 blocks Chk2 activity and potentiates the cytotoxicity of the PARP inhibitors, AG14447 (Item No. 15643) and olaparib (Item No. 10621).2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Caldwell, J.J.,Welsh, E.J.,Matijssen, C., et al. Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. J. Med. Chem. 54(2), 580-590 (2011).
2.Anderson, V.E.,Walton, M.I.,Eve, P.D., et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 71(2), 463-472 (2011).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 442.5 |
| 分子式 | C23H27FN4O4 |
| CAS号 | 1262849-73-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
