NK 252
货号：
19131-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 19131-1mg |
| 描述 | NK 252 is a Nrf2 activator that interacts directly with the domain containing the Nrf2-binding site of Keap1.1 At 1.36 µM, it is reported to activate the NQO1-antioxidant response element in a luciferase reporter gene assay two-fold above background.1 NK 252 has been shown to downregulate the expression of fibrogenic genes, producing antifibrotic effects in a rat model of non-alcoholic steatohepatitis.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shimozono, R.,Asaoka, Y.,Yoshizawa, Y., et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Molecular Pharmacology 84(1), 62-70 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 285.3 |
| 分子式 | C13H11N5O3 |
| CAS号 | 1414963-82-8 |
| 稳定性 | ≥ 2 years |
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